Massimo Caruso is PhD in Respiratory Diseases, Assistant Professor in Biochemistry and Researcher at the Center of Excellence for the acceleration of HArm Reduction (CoEHAR) of the University of Catania. In the early years of his career, his work focused on diagnostic and prognostic biomarkers in asthma and allergies. Over the past decade his interest has moved to assessing the harm induced by cigarette smoke in respiratory and other smoking-related diseases, also using cellular models. He is currently conducting studies on the toxicological impact of electronic nicotine delivery systems (ENDS) for tobacco harm reduction in simple and complex cellular models. Among the various works, he is co-principal investigator of the multicenter study “REPLICA”, which aims to replicate interesting in vitro studies conducted by tobacco companies. The objectives of his studies are to contribute to the definition of critical parameters to be considered for the correct determination of damage in preclinical models and the evaluation of possible improvements to be made to these tools to further reduce their impact on health.
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